The Mustangs have now lost four straight conference games.
Senior guard Victor Joseph led the Mustangs with 11 points in their 57-45 loss to Hawaii.
The Big West Conference welcomes two new universities to their roster, going from nine to 11 schools.
“College basketball is a different physicality and a different type of game,” senior guard Victor Joseph said.
Marcellus Garrick led Cal Poly with 20 points in the game.
Cal Poly wins first road game at Santa Clara Saturday.
The 37-point victory came in the Mustangs first game at Mott Athletics Center this season.
The Mustangs fall to 0-2 after opening the season against two tough Pac-12 opponents.
The Mustangs did not have a player selected to the all-conference team either.
Poly Playbook anchor Kayla Berenson has all the updates you need this week for Cal Poly Athletics.
Junior guard Marcellus Garrick led the Mustangs with 18 points in their win against CSU East Bay.